Thursday, May 15, 2008

Adding Ultrasound Screening to Mammography Brings Benefits, Risks

PROVIDENCE, R.I. [Brown University] — Adding a screening ultrasound examination to routine mammography reveals more breast cancers than mammography alone, according to results of a major new clinical trial. The trial, however, also found that adding an ultrasound exam also increases the rate of false positive findings and unnecessary biopsies.

Results of the clinical trial, conducted by the American College of Radiology Imaging Network (ACRIN) and analyzed by Brown University statisticians, appear in the May 14, 2008 issue of the Journal of the American Medical Association.

"The trial uncovered a significant trade-off with ultrasound screening," said Jeffrey Blume, an associate professor in the Department of Community Health and the deputy director of the ACRIN Biostatistics and Data Management Center at Brown. "While supplemental ultrasound screening uncovers more breast cancers, it also substantially increases the risk of a false positive cancer finding and unnecessary biopsy."

source: Brown University

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